MetaGO result for job id PF02326

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>UniRef100_A0A075DC40/1-164 (164 residues)
MPQLDQFTYLTQFLWLCVFYMTFYVLLYNDGLPKISRIIKLRKRLVSQEKVGAEQSNDRV
EQDVVFKECFQASANYLYSSVSGASKWCKGMVQLANAHKLQRMNKDYVCSLGEISVSQVI
KKNALSTLSPSTYQSTSLASRQTTALNKIYVLRGQKRTLAKIKN

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Proteins with similar structure

Top 10 structural analogs in PDB (as identified by TM-align)

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov.	Download Alignment
1	5lilA	0.55	4.19	0.037	0.811	Download
2	5nikJ	0.55	4.29	0.069	0.823	Download
3	3ljbA	0.54	3.54	0.043	0.695	Download
4	1st6A	0.54	4.30	0.049	0.811	Download
5	4a01A	0.53	4.53	0.062	0.799	Download
6	5xu1M	0.53	4.24	0.050	0.811	Download
7	1tqqA	0.53	3.38	0.050	0.677	Download
8	4whjA	0.51	3.37	0.049	0.683	Download
9	3szrA	0.50	3.63	0.037	0.677	Download
10	1yc9A	0.49	3.74	0.037	0.671	Download

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov. represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted Gene Ontology (GO) Terms

Molecular Function (MF)

GO term	Cscore^GO	Name
GO:0050897	0.11	cobalt ion binding
GO:0017111	0.05	nucleoside-triphosphatase activity
GO:0035639	0.02	purine ribonucleoside triphosphate binding
GO:0032561	0.02	guanyl ribonucleotide binding
GO:0032550	0.02	purine ribonucleoside binding
GO:0046961	0.01	proton-transporting ATPase activity, rotational mechanism
GO:0046933	0.01	proton-transporting ATP synthase activity, rotational mechanism

Download full result of the above consensus prediction.

Click the graph to show a high resolution version.

(a)

Cscore^GO is the confidence score of predicted GO terms. Cscore^GO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.

(b)

The graph shows the predicted terms within the Gene Ontology hierachy for Molecular Function. Confidently predicted terms are color coded by Cscore^GO:

[0.13,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Biological Process (BP)

GO term	Cscore^GO	Name
GO:0009987	0.16	cellular process
GO:0044711	0.07	single-organism biosynthetic process
GO:0009117	0.07	nucleotide metabolic process
GO:1901576	0.06	organic substance biosynthetic process
GO:1901564	0.06	organonitrogen compound metabolic process
GO:0051234	0.06	establishment of localization
GO:0044249	0.06	cellular biosynthetic process
GO:0098542	0.02	defense response to other organism
GO:0071357	0.02	cellular response to type I interferon
GO:0061732	0.02	mitochondrial acetyl-CoA biosynthetic process from pyruvate

Download full result of the above consensus prediction.

Click the graph to show a high resolution version.

(a)

Cscore^GO is the confidence score of predicted GO terms. Cscore^GO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.

(b)

The graph shows the predicted terms within the Gene Ontology hierachy for Biological Process. Confidently predicted terms are color coded by Cscore^GO:

[0.08,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Cellular Component (CC)

GO term	Cscore^GO	Name
GO:0016020	0.03	membrane
GO:0005739	0.02	mitochondrion
GO:0099503	0.01	secretory vesicle
GO:0030027	0.01	lamellipodium
GO:0015629	0.01	actin cytoskeleton
GO:0005925	0.01	focal adhesion
GO:0005915	0.01	zonula adherens
GO:0005886	0.01	plasma membrane

Download full result of the above consensus prediction.

Click the graph to show a high resolution version.

(a)

Cscore^GO is the confidence score of predicted GO terms. Cscore^GO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.

(b)

The graph shows the predicted terms within the Gene Ontology hierachy for Cellular Component. Confidently predicted terms are color coded by Cscore^GO:

[0.14,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Reference:

Chengxin Zhang, Peter L Freddolino, and Yang Zhang. (2018) MetaGO: A Structure and Protein-Protein Interaction Network Based Pipeline for Automated Protein Function Annotations. Journal of Molecular Biology.

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